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Whether clad in blue and red or black, or possessing spider-powers or cosmic ones, Spider-Man stands ready to face any threat! And the threats have never been greater! From his own foes - Venom, Mysterio, the Scorpion and more - to newcomers to his friendly neighborhood like Sabretooth, the Taskmaster, Magneto and the Sentinels, Spidey sure has his hands full! Good thing he's got Mary Jane, Captain America, the Black Cat and the Hulk around to lend a hand! Featuring the pulse-pounding prose of longtime IRON MAN scribe David Michelinie and the groundbreaking artistry of the legendary Todd McFarlane! Collecting AMAZING SPIDER-MAN (1963) #296-329 and material from SPECTACULAR SPIDER-MAN ANNUAL #10.