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Mutants are supposedly evolution's next step, but the High Evolutionary doesn't like where it's headed! All over the world, mutants are robbed of their powers, leaving X-Men and adversaries alike on the edge of defeat! But who is the Evolutionary's mysterious patron, and how is the disempowerment his next step? Plus: threats from the Acolytes, the Neo and more! Guest-starring the New Warriors, X-Force and more than thirty years' worth of robots! Collecting UNCANNY X-MEN #379-380, CABLE (1993) #78, X-FORCE (1991) #101, WOLVERINE (1988) #149 and X-MEN (1991) #99.